Parkinson's disease (PD) is a worsening disorder of central nervous system that affects the movement of the body. In the early stages of PD, the most obvious and common symptoms include movement related such as shaking, rigidity, difficulty in walking, thinking and behavioral problems with dementia in advanced stages. Other symptoms include sensory, sleep and emotional problems. The main motor symptoms are collectively called "parkinsonism", or a "parkinsonian syndrome".

Cure to Parkinson's Disease

This disease affects most commonly in males rather than females and that too above 50. In a survey done in the year 2013, Parkinson Disease was in 53 million patients which resulted in 103,000 deaths worldwide. This disease has been named after English doctor James Parkinson who published the detailed explanation in 1871. Generally, symptoms of PD can be explained in the following manner:

  • Slowness of voluntary movements, especially in the initiation of such movements as walking or rolling over in bed
  • Decreased facial expression, monotonous speech, and decreased eye blinking
  • A shuffling gait with poor arm swings and stopped posture
  • Unsteady balance; difficulty rising from a sitting position
  • Continuous "pill-rolling" motion of the thumb and forefinger
  • Abnormal tone or stiffness in the trunk and extremities
  • Swallowing problems in later stages
  • Lightheadedness or fainting when standing (orthostatic hypotension)

How Mirapex acts on the body?

Mirapex contains Pramipexole as an active ingredient that acts as a full agonist of the dopaminergic receptor. Pramipexole stimulates D3 receptor sites, which in turn excites the direct striatopallidal pathways. It also stimulates D2 receptor sites to inhibit the indirect striatopallidal pathways. The simultaneous modulation of direct and indirect striatopallidal pathways has proved to be much beneficial in the treatment of Parkinson's disease.

How to use Mirapex?

Mirapex is available in the strength of 1mg tablets to be taken orally with ample amount of water. Generally, the dose of the drug is started with a lower amount, gradually increasing the dose. This medicine is useful for decreasing the symptoms of Parkinson's diseases but not to heal the illness. Do not suddenly stop using this medication as it can cause some withdrawal symptoms such as fever, muscle stiffness, changes in consciousness etc. Do not suddenly stop the medication; decrease the dose initially before stopping the medication.  

However, there are some side effects likely to occur while using this medication such as nausea, drowsiness, dizziness, trouble sleeping, headache, and dry mouth.

Precautionary measures:

There are some precautionary measures to be kept in mind while using Mirapex such as:

  • Do not use this medication if you have any allergic reaction to the active ingredient of Mirapex
  • Do not use any type of herbal products, dietary supplements and non-prescription medicines along with the use of this medication
  • Avoid using this medication if you are experiencing any type of kidney or liver disorder, cardiac ailments or any type of sleep disorder
  • Do not use this medication if you are taking any other anti-depressant medication or any medication for blood pressure
  • Do not consume any alcohol drinks  while consuming this medication as it may increase the risk of drowsiness
  • Do not use this medication during pregnancy and breast-feeding
  • If you previously had any dental surgery, you must contact your doctor before using this medication

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