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Tofranil | Generic Imipramine

Tofranil | Generic Imipramine

IMIPRAMINE-(im ip ra meen)

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Quantity Strength Unit Price Price Cart
90 Tablets Tofranil 25MG - Generic $0.10 $8.99
120 Tablets Tofranil 25MG - Generic $0.11 $12.99
30 Tablets Tofranil 75MG - Generic $0.33 $9.99
90 Tablets Tofranil 75MG - Generic $0.30 $26.99


Tofranil is the choice of drug, which is used to treat depression and bed wetting in child above 5 years of age. During the depression, patient behaves abnormally, abrupt eating or sleeping, sad, unhappy, negative thought, violent, fear etc. Bed wetting refers to the unintentional passage of urine on the bed. It is recommended to take this drug orally. The treatment usually continues for 1 to 3 months for bed wetting and in case of depression the treatment is continued up to 4-6 month.

Drug information of Tofranil

In Tofranil, Generic Imipramine is an active constituent. It belongs to the category of Tricyclic antidepressant. Imbalance in the level of neurotransmitter is generally responsible for the cause of depression. It works by preventing the neuronal reuptake of the neurotransmitters nor epinephrine and serotonin. Imipramine acts by inhibiting the effect of acetylcholine in the urinary bladder.

Why to take Tofranil?

It is indicated in the treatment of depression and enuresis (bed wetting at night).

Contraindications of Tofranil

The use of this drug in contraindicated in certain condition

  • In case of any allergy to Tofranil or any of its ingredients.
  • If you have taken any monoamine oxidase inhibitors such as isocarboxacid.
  • After any heart surgery recovery.

Tofranil Drug interaction

  • Avoid intake of certain drug while taking Tofranil
  • Avoid Anti-parkinson’s drugs such as Valproic acid, Levodopa,
  • Avoid intake of MAO inhibitors such as Linezolid, Moclobemide methylene blue,
  • Avoid intake of Antidepressants drugs such as Fluoxetin, Venlafaxine

Storage of Tofranil

  • Store in a cool dry place at room temperature. 
  • Keep away from the reach of the children.

Dosage of Tofranil

In adults for the treatment of depression the maximum recommended dose is 300mg. It is recommended taking 25mg of this drug three times in a day with or without food.

  • For the treatment of bed wetting, the normal dose for children aged 5-8 years is 20 to 30 mg.
  • For children aged 9-12 years the dose is 25 to 50 mg every day and for children aged over 12 years, the dose is up to 75 mg every day.

What you do in case of missed dose?

Follow your dosage regimen strictly. If you have forgotten to take a dose then consume it as soon as you get remembered. If it is getting the time for the next dose then omit it and continue with your regular doses.

What you do in case of overdose of Tofranil?

Overdosing of Tofranil can be serious. So take the dose as recommended. Visit your nearest hospital if overdosing occurs.

Side effects Tofranil

Some common side effects of this drug include anxiety, Disturbed sleep, trembling, Nausea Sores in the mouth or on the Tongue, dizziness, Headache, Increased sensitivity to the sun, Hair loss. Some serious side effects include yellow color to the skin, eye pain, difficulty in speaking, irritability, Confusion, hallucinations, regular passing of large amounts of urine.


  • Avoid driving or any machinery work as it may impair thought and cause dizziness.
  • Avoid consumption of alcohol while taking this drug, as it causes dizziness.
  • Wear protective cloth or sunscreen while taking this drug, as this drug makes the skin more sensitive.

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