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Calcipotriene (kal-si-poe-TRY-een) Topical

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Quantity Strength Unit Price Price Cart
1 Tube Dovonex Ointment (30 gm) $91.00 $91.00
3 Tubes Dovonex Ointment (30 gm) $91.00 $273.00


Dovonex is a form of vitamin D. It is concerned with the growth and development of skin cells. It is the skin condition in which red and scaly patches develops on your skin. It mainly effects over your elbows, knees, the scalp, and the lower part of your back. The size of these patches may vary in size and the main aim is to clear the plaque as much as possible.

Mechanism of action of Dovonex

Calcipotriene stops the keratinocyte production and stimulates the unimportant breakdown of keratinocyte. Keratocytes cells are found on the outer layer of the epidermis and it acts as a barrier against several pathogens like bacteria, fungus, viruses, and parasites. Thus, calcipotriol reverses and inhibits the nonstandard keratinocyte that causes irritation and shows a vitamin-D like activity. It happens when calcipotriol binds with a cellular receptor. Calcitriol in psoriasis acts by inhibiting the production of the keratinocyte and stir up with the other inflammatory cells.

Contraindications of Dovonex

There are certain conditions when you must avoid while using Dovonex:

  • Patients who are hypersensitive to Calcipotriene or another medicament of the Dovonex cream should keep away from this formulation.
  • Do not apply this cream if you suffering from skin conditions like injured skin, sunburns or cut or laceration (scratch).
  • Dovonex cream is restricted to be applied on the face.

 Drug interaction of Dovonex cream

Dovonex is not to be used along with the combination of Vitamins or a mineral supplement that contains calcium or vitamin D as it may interact with the action of the drug.

How should you apply Dovonex Cream?

Clean the skin where to apply the Dovonex cream. You should use only on the affected area of the skin.

In case of Skipped dose of Dovonex cream

If the patient missed to apply a dose of Dovonex cream, use it as soon as you remember. But if it is near to the time for your next dose then don not apply large amount at once to match up the missed dose.

Storage environment of Dovonex cream

The Dovonex cream should be stored in an air tight container. Protect it from heat light and moisture. Do not freeze this drug. Keep away from the reach of children.

Adverse effects of Dovonex cream:

Burning sensation, skin rashes, itching and redness of the skin, dryness of skin, stinging, dermatitis.

Important safety measures you must keep in mile while before applying this drug:

  • This medication is not to be used in the children under the age of 12 years.
  • Pregnant women and lactating mothers should use this drug with some cautions.
  • Always use sunscreen lotion or wear a sun protecting clothes when you are exposed to the sun.
  • When you are on the treatment with Dovonex, Don’t use any other cosmetic products. 

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