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Levothyroxine Sodium

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Quantity Strength Unit Price Price Cart
50 Tablets Levothroid 50mcg - Generic $0.26 $12.99
100 Tablets Levothroid 25mcg - (Bottle of 100 Tablets) $0.14 $13.99
100 Tablets Levothroid 75mcg - Bottle of 100 Tablets $0.14 $13.99
100 Tablets Levothroid 100mcg $0.14 $13.99
100 Tablets Levothroid 125mcg - Bottle of 100 Tablets $0.15 $14.99
100 Tablets Levothroid 150mcg Bottle of 100 Tablets $0.15 $14.99
100 Tablets Levothroid 200mcg (Bottle of 100 Tablets) $0.14 $13.99


Synthroid is a man-made thyroid hormone that is used to treat a condition called as hypothyroidism which is usually associated with inflammation of thyroid gland (thyroiditis). This medication is most commonly meant to replace a hormone that is made by the thyroid gland.

Mechanism of action of Synthroid:

Synthroid with an active ingredient Levothyroxine sodium acts like endogenous thyroid hormone thyroxin (T4, a tetra-iodinated tyrosine derivative). In liver and kidney, T4 is converted to T3, the active metabolite. In order to increase solubility, the thyroid hormones attach to thyroid hormone binding proteins, thyroxin-binding globulin, and thyroxin-binding prealbumin (transthyretin). Transport and binding to thyroid hormone receptors in the cytoplasm and nucleus then take place. Thus by acting as a replacement for natural thyroxin, symptoms of thyroxin deficiency are relieved.

How to administer Synthroid?

Synthroid is available as 25mg, 50mg, 75mg, 100mg, 125mg, 150mg and 200mg strength tablets. These tablets are to be taken by mouth with plenty of water. It is usually taken empty stomach and particularly an hour before breakfast. You are advised to take this medication as prescribed by your doctor. Do not crush or chew the tablet. Swallow it as a whole. Doctor usually starts with a lower dose of the drug gradually increasing the dose.

However, there are some side effects likely to occur while using Synthroid such as chest pain, decreased urine output, fatigue, fainting, fever, increased blood pressure, shortness of breath, sweating, and tremors.

Missed Dose: In case the dose is missed, try to take it as soon as possible and particularly empty stomach.

Overdose: In the case of overdose, consult your physician as soon as possible, else seek medical attention immediately.

Contraindications of using Synthroid:

There are some contraindications to be kept in mind while using Synthroid such as-

  • Avoid using calcium carbonate products while using this medication
  • Do not use ferrous sulphate iron supplement while using Synthroid
  • Avoid using any sort of Antacids with this medication
  • Do not use Soya products while using this medication
  • Avoid walnut and high fiber foods with use of this medication

Drug interactions for Synthroid:

There are some drugs likely to interact with Synthroid. You must inform your doctor before using following medications: Amiodarone (Cordarone, Pacerone); amphetamines; anticoagulants ('blood thinners') such as Warfarin (Coumadin); aspirin or aspirin-containing products and other nonsteroidal anti-inflammatory drugs; beta-blockers such as metoprolol (Lopressor), Propranolol (Inderal) or Timolol (Timoptic); Carbamazepine (Equetro, Tegretol); corticosteroids such as dexamethasone; digoxin (Lanoxin); estrogens; Furosemide (Lasix); imatinib (Gleevec); insulin or other medications to treat diabetes; lithium (Lithobid); maprotiline; oral contraceptives; Phenobarbital; Phenytoin (Dilantin, Phenytek); rifampin (Rifater, Rifamate, Rifadin); selective serotonin reuptake inhibitors (SSRIs) such as sertraline (Zoloft); theophylline (Theodur); and tricyclic antidepressants such as Amitriptyline (Elavil).

Storage Conditions for Synthroid:

This medication is to be stored at room temperature; to be kept away from sunlight and moisture. Keep out of reach from children.

Precautionary measures:

There are some precautionary measures to be kept in mind while using Synthroid such as-

  • You must inform your doctor if you are using any non-prescription medicines, dietary or herbal supplements
  • Avoid using alcohol and tobacco products while using this medication
  • Not recommended to be used by individuals less than 6 years of age

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